BREAKING NEWS : STUDIES CONFIRM BIOFORTIFICATION OF TUBERS (Sweet Potatoes)

A study published today in the Journal of Nutrition provides conclusive evidence that orange sweet potato (OSP) provided significant amounts of vitamin A to malnourished Ugandan children and women and that a modest improvement in vitamin A levels in the body was measurable in some cases.Vitamin A deficiency (VAD) is a major public health concern in poorer countries and accounts for more than 600,000 deaths a year among children under five years of age. In Africa, VADprevalence is estimated at 42% among children under five.Uganda is among the African countries reported to be at high risk, with 28% of children and 23% of women estimated to be vitamin A deficient. VAD can impair immunity and cause eye damage that can lead to blindness and even Annually, up to 500,000 preschool children go blind from VAD, and about two-thirds will die within months of going blind.

Biofortification is the process of breeding new varieties of foods crops that contain higher amounts of nutrients to improve nutrition and public health. Agricultural approaches, such as biofortification, are now being looked upon to fill the nutritional gap for vitamin A and other nutrients.Traditionally, white or yellow sweet potato varieties are grown and eaten in Africa, but these provide little, or no, vitamin A. OSP was conventionally bred, not just to provide more vitamin A but also to be high yielding and drought tolerant.From 2007–2009, HarvestPlus and its partners disseminated new OSPvarieties to more than 10,000 farming households in Uganda for whom sweet potato is a key staple food.

The project provided OSP vines for farmers to grow, as well as extension services and nutritional information so that farmers could incorporate OSP into their cropping systems. Since sweet potato is available for about 10 months a year, it can be a rich and steady source of vitamin A.The project resulted in 61% of households adopting the vitamin A-rich OSP to grow on their farms. They were also willing to substitute more than one-third of their traditional white and yellow sweet potato consumption with OSP. This level of substitution was enough to push large numbers of children and women over the threshold, ensuring that their daily requirements for vitamin A were met.Vitamin A intake increased by two-thirds for older children and nearly doubled for younger children and women by project end. For children 6–35 months, who are especially vulnerable, OSP contributed more than 50% of their total vitamin A intake.The high prevalence of inadequate vitamin A intake among a subset of children 12–35 months who were no longer breastfeeding fell from nearly 50% to only 12% as a result of the project. This is a very positive finding as young children who have recently stopped breastfeeding are at higher risk of VAD. This is because breast milk has been their primary source of vitamin A and their vitamin A needs continue to be high.Researchers were also able to measure a small positive impact of eating OSPon the amount of vitamin A in the blood among children 5–7 years that had lower levels of vitamin A at the start of the project. At project end, researchers also found that women who got more vitamin A from OSP had a lower likelihood of having marginal VAD. (VAD was unexpectedly low among the women sampled in this study, thus making it harder to detect changes.)“Overall, these results add to the growing evidence base that OSP provides large amounts of vitamin A in the diet,” says Dr. Christine Hotz, former HarvestPlus Nutrition Head who led the nutrition study. “We were also able to show a modest increase in vitamin A blood levels among children, despite this being challenging to measure given the changing nutritional landscape over two years under real-world conditions.”This project was undertaken concurrently in Mozambique where results showed even higher levels of adoption—and consumption—of OSP by vulnerable households.“We now have evidence from two very different countries and contexts that show that farming households are willing to adopt OSP, incorporate it in their diets, and get the vitamin A that they need,” says senior IFPRI economist, Dr. Daniel Gilligan.HarvestPlus is now scaling-up OSP to reach another 225,000 households by 2016.

The International Potato Center (CIP) plans to scale-up OSP to reach more than 600,000 households in 10 countries by 2015, including 120,000 households in Mozambique.About the ProjectFrom 2007-2009, HarvestPlus and its partners disseminated orange sweet potato—to see if VAD could be reduced—to more than 24,000 households in Mozambique and Uganda. HarvestPlus leads a global effort to breed and disseminate micronutrient-rich staple food crops to reduce hidden hunger in malnourished populations. It is part of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH). It is coordinated by the International Center for Tropical Agriculture (CIAT) and the International Food Policy Research Institute (IFPRI).Journal Article Introduction of β-Carotene–Rich Orange Sweet Potato in Rural Uganda Results in Increased Vitamin A Intakes among Children and Women and Improved Vitamin A Status among Children. Journal of Nutrition.Partners in Uganda Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA) and Regional Potato and Sweetpotato Improvement Network in Eastern and Central Africa (PRAPACE), Farming for Food and Development Eastern Uganda (FADEP-EU), International Food Policy Research Institute, International Potato Center (CIP), Makerere University, National Agricultural Research Organization, Natural Resources Institute, University of Greenwich, Uganda Bureau of Statistics, Volunteer Efforts for Development Concerns (VEDCO).

Thanks go to the district and provincial officials in Uganda (Bukedea, Kamuli, Mukono) and to the many people of Uganda who participated in the project and the research study.DonorsThe Bill and Melinda Gates Foundation provided a direct grant that made this research possible. Additional HarvestPlus core funding was also used to support this work, which included support from (in alphabetical order): Denmark (DANIDA), Sweden (SIDA), the Syngenta Foundation, the United Kingdom (DFID), the United States (USAID), and the World Bank.

Media ContactYassir Islam, Head of Communications (Washington, D.C.) y.islam@cgiar.orgTel: + 1 (202) 862-560